HORDB

ID: hor001061
Uniprot ID: Q9BH17
Protein name: FMRFamide-related peptide
Gene name: flp-2
Organism: Globodera pallida (Potato cyst nematode)
Family: FMRFamide related peptide family
Source: animal
Expression: the lumbar ganglia and pre-anal ganglia along with the BDU neurones and a number of cells in the retrovesicular ganglion
Disease: NA
Comments: NA
Taxonomy: Globodera (genus), Heteroderinae (subfamily), Heteroderidae (family), Tylenchoidea (superfamily), Tylenchomorpha (infraorder), Tylenchina (suborder), Rhabditida (order), Chromadorea (class), Nematoda (phylum), Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: NA
GO BP: NA
GO CC: NA

Sequence: KNKFEFIRF
Length: 9
Propeptide: MIQQIPTALLLVTLATALLMLSGVKTNAQNAHLLVERDFGNAERVNDRPMNGVDGEVIDKMESRLLGALELLQTYRDAPIVPKFTVKRKNKFEFIRFGKRRR
Signal peptide: MIQQIPTALLLVTLATA
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Function: Regulation of both dorsal and ventral body wall muscles, the musculature of the vulva and in the function of a number of sensory structures in both the head and tail
Mechanism: NA
Cross BBB: NA
Target: NA
Target Unid: NA
IC50: NA
EC50: NA
ED50: NA
kd: NA
Half life: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor001061_AF2.pdb

hor001061_ESM.pdb

Mass:	137132	Formula:	C60H89N15O13
Absent amino acids:	ACDGHLMPQSTVWY	Common amino acids:	F
pI:	10.79	Basic residues:	3
Polar residues:	1	Hydrophobic residues:	4
Hydrophobicity:	-71.11	Boman Index:	-2561
Half-Life:	1.3 hour	Half-Life Yeast:	3 min
Half-Life E.Coli:	2 min	Aliphatic Index	43.33
Instability Index:	3520	Extinction Coefficient cystines:	0
Absorbance 280nm:	0

PubMed ID: 12117492
Title: Localisation of Globodera Pallida FMRFamide-related Peptide Encoding Genes Using in Situ Hybridisation